Input and Output ================ Inputs ------ - fragment file or Cell Ranger matrix directory; when using a fragment file, the workflow sorts it internally by barcode and genomic position by default - reference genome FASTA - blacklist BED file Outputs ------- - ``outdir/outs/result_table.tsv.gz`` with the consensus Holmes+Watson CNV table - ``outdir/count_matrix.h5ad`` with the filtered count matrix used for inference - ``outdir/parameter_configuration.txt`` with the run configuration - ``outdir/binned_genome.csv`` with the genome bins and GC annotations - ``outdir/breakpoints.csv`` with the detected breakpoints per cell - ``outdir/clusters.json`` with the inferred segment clusters per cell - ``outdir/outs/Karyogram.png`` when plotting is enabled - ``outdir/outs/integer_states.tsv.gz`` with integer CNV states - ``outdir/outs/continuous_scores.tsv.gz`` with continuous CNV scores - ``outdir/outs/result_table_holmes.tsv.gz`` with Holmes-mapped CNV states - ``outdir/outs/result_table_watson.tsv.gz`` with Watson-mapped CNV states - ``outdir/outs/scaling_factors.tsv.gz`` with per-cell scaling factors